Auto-immuunziekten

Hoeveel procent heeft auto-immuunziekte(n)?

44 van de 196 vrouwen heeft één of meerdere auto-immuunziekten = 22,45%. Dit wijst een onderzoek van het Meldpunt uit. Zie illustratie onderaan op deze pagina. Deze cijfers komen overeen met een onderzoek onder 2 miljoen vrouwen. >> 

Omdat bijna alle vrouwen voldoen aan de criteria voor ASIA is het aantal auto-immuunziekten waarschijnlijk hoger. >>

Factoren - oorzaken

Siliconen zijn niet de enige directe oorzaak van het ontstaan van een auto-immuunziekte, maar er zijn meer factoren die een rol spelen. Het is een combinatie van verschillende factoren die tot een auto-immuunziekte leiden:

Onderzoek onder 2 miljoen vrouwen

Eén onderzoek is gedaan in 2018 onder 2 miljoen vrouwen wereldwijd  >> en toont een verhoogde kans aan op de volgende auto-immuunziekten voor vrouwen met siliconen borstimplantaten:

Boek: Breast implants, everything you need to know

Op blz. 92 een goed uitleg over de relatie met auto-immuunziekten.

Vrij vertaald: Er is bewijs dat de beschermende enzymen van het lichaam de siliconen envelop afbreekt; dan slokken de macrofagen - de immuunsysteemcellen - de siliconendeeltjes op. De macrofagen voeren de giftige siliconen door het hele lichaam en als reactie hierop komen er immuunsysteemstoffen in het lichaam vrij genaamd cytokines. Deze omvatten interferon en tumor necrose factor, die verantwoordelijk zouden kunnen zijn voor het veroorzaken van de griepachtige symptomen en andere symptomen van ontsteking, zoals spierpijn, gewrichtspijn, geleden door een aantal vrouwen met implantaten.

Wetenschappelijke onderzoeken

A Comparative Analysis of Local and Systemic Immunological Biomarkers in Females With Breast Implants and Capsular Contracture 2024 >> 

Biofilm derived oxylipin 10-HOME mediated immune response in women with breast implants  2023 >> 

Investigating Immunomodulatory Biomaterials for Preventing the Foreign Body Respons 2023 >> 

Autoimmune autonomic nervous system imbalance and conditions: Chronic fatigue syndrome, fibromyalgia, silicone breast implants, COVID and post-COVID syndrome, sick building syndrome, post-orthostatic tachycardia syndrome, autoimmune diseases and autoimmune/inflammatory syndrome induced by adjuvants. 2023 >>  (zenuwstelsel)

Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) in 2023☆ >> 

Breast Implant-Associated Immunological Disorders. 2022 >> 

Silicone Breast Implants and Lupus 2022 >> 

Autoimmune Disease and Breast Implants: Systematic Review of Outcomes. 2021 >> 

Think autoimmunity, breath autoimmunity, and learn autoimmunity. 2019 >>

Hyperstimulation of Adaptive Immunity as the Common Pathway for Silicone Breast Implants, Autoimmunity, and Lymphoma of the Breast. 2019 >>

Silicone breast implants and the risk of autoimmune/rheumatic disorders: a real-world analysis. okt 2018 (2 miljoen deelnemers, studie van 20 jaar) 2018 >>

Autoinflammatory/autoimmunity syndrome induced by adjuvants (ASIA; Shoenfeld's syndrome): A new flame. 2018 >>

Silicone breast implants and the risk of autoimmune diseases: real world analysis ( 2 miljoen vrouwen) 2018 >>

Silicone implant incompatibility syndrome: Mimicking metastases on fluoro-deoxy-glucose positron emission tomography–computed tomography in a treated case of carcinoma breast. 2018 >>

Mechanisms of Breast Implant Toxicity: Will the Real Ringmaster Please Stand Up. 2017 >> 

Identification of hub genes related to silicone-induced immune response in rats. 2017 >>

Is explantation of silicone breast implants useful in patients with complaints? 2016 >>

Long-Term Health Outcomes in Women with Silicone Gel Breast Implants. 2015 >>

Microscopic polyangiitis following Silicone Exposure from Breast Implantation. 2014 >> 

The imuunologic respons of breast implant: The roll of cells and cytokines in the periprosthetic capsules and their involvement in the onset ofautoimmune diseases. 2013 >>

Applications of polymeric adjuvants in studuing auto-immune responses and vaccinations against infection diseases. 2013 >>

Silicone implant incompatibility syndrome (SIIS): A frequent cause of ASIA (Shoenfeld’s syndrome) 2013 >>

What is ASIA? An interview with Jehuda Shoenfeld. 2013 >>

T-regulatoire cellen en Th17 cellen peri-siliconen implantaat capsulaire fibrose. 2012 >>

The spectrum of ASIA: ‘Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants’. 2012 >>

Human adjuvant disease induced by foreign substances: a new model of ASIA (Shoenfeld's syndrome. 2012 >>

Autoimmune syndrome induced by adjuvants (ASIA) in the Middle East: morphea following silicone implantation. 2012 >>

Gulf War syndrome as a part of the autoimmune (autoinflammatory) syndrome induced by adjuvant (ASIA). 2012>>

Case report: localized scleroderma of the breast after saline implant rupture. 2011 >>

ASIA: A New Way to Put the Puzzle Together. 2011 >>

‘ASIA’ - Autoimmune/inflammatory syndrome induced by adjuvants: even and odd. 2011 >>

'ASIA' - autoimmune/inflammatory syndrome induced by adjuvants. 2011 >>

ASIA or Shoenfeld's syndrome: a novel autoimmune syndrome? 2010 >>

The sick building syndrome as a part of the autoimmune (auto-inflammatory) syndrome induced by adjuvants. 2011 >>   2015 >> 

The association between silicone implants and both antibodies and autoimmune diseases. 2008 >>

Altered systemic serological parameteres in patients with silicone mammary implants. 2008 >>

Identification and dynamics of proteins adhering to the surface of medical silicones in vivo and in vitro. 2007 >>

Simultaneous analysis of multiple serum proteins adhering to the surface of medical grade polydimethylsiloxane elastomers. 2007 >>

In vitro interaction between silicone gel and human monocyte-macrophages. 2005 >>

Microscopic polyangiitis after silicone breast implantation 2005 >>

Infection, vaccines and other environmental triggers of autoimmunity. 2005 >>

Cellular and molecular composition of fibrous capsules formed around silicone breast implants with special focus on local immune reactions.2004 >>

A comparison of autoantibody production in asymptomatic and symptomatic women with silicone breast implants. 1999 >>

Silicone gel filled breast and testicular implants capsules: A Histologic and immunophenotypic study. 1999 >>

Cellular immune reactivities in women with silicone breast implants: a preliminary investigation. 1997 >>

Immunologic stimulation of T lymphocytes by silica after use of silicone mammary implants. 1996 >>

Phenotype of Lymphocytes Associated with the Inflammatory Reaction to Silicone Gel Breast Implant. 1996 >>

Multiple autoantibodies in patients with silicone breast implants.1995 >>

Immunopathologic Effects of Silicone Breast Implants. 1994 >>

Serum antinuclear antibodies in women with silicone breast implants. 1995 >>

A profile of symptomatic patients with silicone breast implants: A Sjögrens-like syndrome. 1994 >>

Autoimmune connective tissue disease and connective tissue disease-like illnesses after silicone gel augmentation mammoplasty.1994 >>

Association between Bovine Collagen Dermal Implants and a Dermatomyositis or a Polymyositis-like Syndrome. 1993 >>

Silicone-reactive disorder: a new autoimmune disease caused by immunostimulation and superantigens. 1993 >>

Anti-collagen autoantibodies are found in women with silicone breast implants. 1993 >>

Antinuclear autoantibodies in women with silicone breast implants.1992 >>

Immune functional impairment in patients with clinical abnormalities and silicone breast implants. 1992 >>

Human adjuvant disease: remission of silicone induced autoimmune disease after explanation of breast augmentation. 1990 >>

Systemic Sclerosis after Augmentation Mammoplasty with Silicone Implants. 1989 >>